The department of urology, LTMMC & LTMH Sion was established on 1st January 1978. It was the first urology department among the three municipal medical colleges in Mumbai. The department has a separate OPD & a 40 bedded ward.  Lithotripsy facilities and instruments for Endourology were also acquired. On 15th July 1980 recognition was granted by the University of Bombay for the degree of M.Ch. Urology. Three registrations were granted as there were three teachers namely Dr.S.D.Bapat, Dr.R.M.Prabhu and Dr.C.T.Patel. The department was headed by Dr.V.D.Trivedi from 1991 to sept.2004, Dr.Sujata Patwardhan from oct 2004 to july 2009  & then from  august  2009 to april 2014 by     Dr. Jayesh Dhabalia. Present head of the department is Prof. Dr.Ajit S. Sawant.
To deal with the increasing influx of patients, urology OPD was conducted twice weekly. The first kidney transplant was performed in Bombay in 1977 and subsequently a regular transplant programme was established at LTMG Hospital. The department of urology has been carrying out live related kidney transplantation regularly. On 27th March 1997, the first cadaver kidney transplantation in the state of Maharashtra was carried out by us. LTMGH is designated as the Zonal Co-Ordination Centre for Cadaver Transplant in Maharashtra. We have a separate transplant OPD on every Saturday.
A separate Andrology OPD was established in 1992.

During last year OPD attendance was 7600 patients and 1450 operative procedures were carried out. patients per year. Urology Department of LTMGH also provides urology  care to Half Way Home established by the Paraplegia Foundation.
Since 1993 PCNL has been carried out regularly. Various sub-specialties of urology like adult and pediatric reconstructive urology, Female Urology, Uro-oncology, Endourology, Infertility & Impotence counseling and treatment are well established.

The yearly intake capacity for course M.Ch urology is four.

The department of Urology have Holmium Laser machine, flexible endoscopy, SWL machine, 2 C-arm machines, Endovision camera, TRUS machine, Laparoscopy set, Uroflowmeter, UDS machine for the better service to patients and better training to students.